Fetal Programming of Adult Glucose Homeostasis in Mice
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چکیده
منابع مشابه
Fetal Programming of Adult Glucose Homeostasis in Mice
BACKGROUND Emerging evidence suggests that dietary soy and phytoestrogens can have beneficial effects on lipid and glucose metabolism. We have previously shown that male mice fed from conception to adulthood with a high soy-containing diet had reduced body weight, adiposity and a decrease in glucose intolerance, an early marker of insulin resistance and diabetes. OBJECTIVES The purpose of thi...
متن کاملFetal programming and adult health.
Low birthweight is now known to be associated with increased rates of coronary heart disease and the related disorders stroke, hypertension and non-insulin dependent diabetes. These associations have been extensively replicated in studies in different countries and are not the result of confounding variables. They extend across the normal range of birthweight and depend on lower birthweights in...
متن کاملGlucose catabolism in fetal and adult heart.
The cells of growing and developing organisms are generally characterized by a higher rate of protein synthesis than is found in the cells of mature forms, and it has been shown repeatedly (1) that increases in rate of protein synthesis are associated with higher RNA content. It might then be expected that enaymes necessary for ribose synthesis would be in greater supply in rapidly proliferatin...
متن کاملAcute nutritional stress during pregnancy affects placental efficiency, fetal growth and adult glucose homeostasis
Exposure to maternal malnutrition impairs postnatal health. Acute nutritional stress is less clearly implicated in intrauterine programming. We studied the effects of stressing pregnant mothers on perinatal growth and adult glucose homeostasis. We compared one group ("stressed", mothers fasted for 16 hours) with controls ("unstressed"). We found that fasting stress had adverse effects on the we...
متن کاملCALL FOR PAPERS Fetal Physiological Programming Fetal origins of adult vascular dysfunction in mice lacking endothelial nitric oxide synthase
Longo, Monica, Venu Jain, Yuri P. Vedernikov, Radek Bukowski, Robert E. Garfield, Gary D. Hankins, Garland D. Anderson, and George R. Saade. Fetal origins of adult vascular dysfunction in mice lacking endothelial nitric oxide synthase. Am J Physiol Regul Integr Comp Physiol 288: R1114–R1121, 2005. First published December 30, 2004; doi:10.1152/ajpregu.00367.2004.— Epidemiological studies have s...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2009
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0007281